Food-dependent set-up of the DiDGI® dynamic in vitro system: Correlation with the porcine model for protein digestion of soya-based food

The present study compared in vivo protein digestion a miniature pig model with the dynamic vitro system DiDGI®, using three digestive compartments (stomach, duodenum, and jejunum + ileum). Two soya-based meals—commercial soya milk tofu—were studied, each same macronutrient content but different macrostructures. Our aim was to first deduce from experiments pigs key parameters such as gastric pH, stomach emptying kinetics, intestinal transit time, order design relevant set-up for system. Then, we samples collected at fixed sampling times both models regarding values related proteolysis. We observed similar evolutions of peptide distribution duodenal proteolysis between models. Overall, apparent ileal digestibility nitrogen differences two meals were conserved